Classification of age groups using functional connectivity

This example compares different kinds of functional connectivity between regions of interest : correlation, partial correlation, and tangent space embedding.

The resulting connectivity coefficients can be used to discriminate children from adults.In general, the tangent space embedding outperforms the standard correlations: see Dadi et al.[1] for a careful study.

Load brain development fMRI dataset and MSDL atlas

We study only 30 subjects from the dataset, to save computation time.

from nilearn.datasets import fetch_atlas_msdl, fetch_development_fmri
from nilearn.plotting import plot_connectome, plot_matrix, show

development_dataset = fetch_development_fmri(n_subjects=30)
[fetch_development_fmri] Dataset found in
/home/runner/nilearn_data/development_fmri
[fetch_development_fmri] Dataset found in
/home/runner/nilearn_data/development_fmri/development_fmri
[fetch_development_fmri] Dataset found in
/home/runner/nilearn_data/development_fmri/development_fmri
[fetch_development_fmri] Downloading data from
https://osf.io/download/5c8ff3ea4712b400183b70b7/ ...
[fetch_development_fmri]  ...done. (1 seconds, 0 min)

[fetch_development_fmri] Downloading data from
https://osf.io/download/5c8ff3eb2286e80019c3c194/ ...
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
https://osf.io/download/5cb46e9b39926900190fad5c/ ...
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[fetch_development_fmri] Downloading data from
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[fetch_development_fmri] Downloading data from
https://osf.io/download/5c8ff3884712b400183b7023/ ...
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[fetch_development_fmri] Downloading data from
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We use probabilistic regions of interest (ROIs) from the MSDL atlas.

msdl_data = fetch_atlas_msdl()
msdl_coords = msdl_data.region_coords
n_regions = len(msdl_coords)
print(
    f"MSDL has {n_regions} ROIs, "
    f"part of the following networks:\n{msdl_data.networks}."
)
[fetch_atlas_msdl] Dataset found in /home/runner/nilearn_data/msdl_atlas
MSDL has 39 ROIs, part of the following networks:
['Aud', 'Aud', 'Striate', 'DMN', 'DMN', 'DMN', 'DMN', 'Occ post', 'Motor', 'R V Att', 'R V Att', 'R V Att', 'R V Att', 'Basal', 'L V Att', 'L V Att', 'L V Att', 'D Att', 'D Att', 'Vis Sec', 'Vis Sec', 'Vis Sec', 'Salience', 'Salience', 'Salience', 'Temporal', 'Temporal', 'Language', 'Language', 'Language', 'Language', 'Language', 'Cereb', 'Dors PCC', 'Cing-Ins', 'Cing-Ins', 'Cing-Ins', 'Ant IPS', 'Ant IPS'].

Region signals extraction

To extract regions time series, we instantiate a NiftiMapsMasker object and pass the atlas the file name to it, as well as filtering band-width and detrending option.

from nilearn.maskers import NiftiMapsMasker

masker = NiftiMapsMasker(
    msdl_data.maps,
    resampling_target="data",
    t_r=development_dataset.t_r,
    detrend=True,
    low_pass=0.1,
    high_pass=0.01,
    memory="nilearn_cache",
    memory_level=1,
    standardize_confounds=True,
    verbose=1,
)

Then we compute region signals and extract useful phenotypic information.

[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
________________________________________________________________________________
[Memory] Calling nilearn.image.resampling.resample_img...
resample_img(<nibabel.nifti1.Nifti1Image object at 0x7f92c3499270>, interpolation='linear', target_shape=(50, 59, 50), target_affine=array([[   4.,    0.,    0.,  -96.],
       [   0.,    4.,    0., -132.],
       [   0.,    0.,    4.,  -78.],
       [   0.,    0.,    0.,    1.]]))
_____________________________________________________resample_img - 0.2s, 0.0min
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar128_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92c349bc10>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar128_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar128_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 1.2s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar126_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92e6f599c0>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar126_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar126_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 1.0s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar125_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92e6f599c0>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar125_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar125_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 1.0s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar124_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e200>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar124_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar124_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 1.0s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar123_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92e6f58610>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar123_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar123_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 1.0s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar127_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779c040>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar127_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar127_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar024_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e200>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar024_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar024_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar023_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e410>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar023_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar023_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar022_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779c040>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar022_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar022_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar021_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e200>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar021_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar021_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar020_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e410>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar020_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar020_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar019_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779c040>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar019_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar019_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 1.0s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar018_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e200>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar018_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar018_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar017_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e410>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar017_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar017_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar016_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779c040>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar016_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar016_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar001_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e200>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar001_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar001_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar013_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e410>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar013_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar013_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar012_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779c040>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar012_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar012_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar011_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e200>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar011_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar011_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar010_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e410>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar010_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar010_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar009_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779c040>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar009_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar009_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar008_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e200>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar008_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar008_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar007_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e410>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar007_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar007_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar006_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779c040>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar006_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar006_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 0.9s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar005_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e200>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar005_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar005_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 1.0s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar004_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e410>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar004_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar004_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 1.0s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar003_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779c040>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar003_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar003_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 1.0s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar002_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e200>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar002_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar002_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 1.0s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar014_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779e410>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar014_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar014_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 1.0s, 0.0min
[NiftiMapsMasker.wrapped] Loading regions from
'/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii'
[NiftiMapsMasker.wrapped] Resampling regions
[NiftiMapsMasker.wrapped] Finished fit
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

________________________________________________________________________________
[Memory] Calling nilearn.maskers.base_masker.filter_and_extract...
filter_and_extract('/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar015_task-pixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz',
<nilearn.maskers.nifti_maps_masker._ExtractionFunctor object at 0x7f92d779c040>, { 'allow_overlap': True,
  'clean_args': None,
  'clean_kwargs': {},
  'cmap': 'CMRmap_r',
  'detrend': True,
  'dtype': None,
  'high_pass': 0.01,
  'high_variance_confounds': False,
  'keep_masked_maps': False,
  'low_pass': 0.1,
  'maps_img': '/home/runner/nilearn_data/msdl_atlas/MSDL_rois/msdl_rois.nii',
  'mask_img': None,
  'reports': True,
  'smoothing_fwhm': None,
  'standardize': False,
  'standardize_confounds': True,
  't_r': 2,
  'target_affine': None,
  'target_shape': None}, confounds=[ '/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar015_task-pixar_desc-reducedConfounds_regressors.tsv'], sample_mask=None, dtype=None, memory=Memory(location=nilearn_cache/joblib), memory_level=1, verbose=1, sklearn_output_config=None)
[NiftiMapsMasker.wrapped] Loading data from
'/home/runner/nilearn_data/development_fmri/development_fmri/sub-pixar015_task-p
ixar_space-MNI152NLin2009cAsym_desc-preproc_bold.nii.gz'
[NiftiMapsMasker.wrapped] Extracting region signals
[NiftiMapsMasker.wrapped] Cleaning extracted signals
/home/runner/work/nilearn/nilearn/examples/03_connectivity/plot_group_level_connectivity.py:67: FutureWarning:

boolean values for 'standardize' will be deprecated in nilearn 0.15.0.
Use 'zscore_sample' instead of 'True' or use 'None' instead of 'False'.

_______________________________________________filter_and_extract - 1.0s, 0.0min
Data has 24 children.

ROI-to-ROI correlations of children

The simpler and most commonly used kind of connectivity is correlation. It models the full (marginal) connectivity between pairwise ROIs. We can estimate it using ConnectivityMeasure.

from nilearn.connectome import ConnectivityMeasure

correlation_measure = ConnectivityMeasure(kind="correlation", verbose=1)

From the list of ROIs time-series for children, the correlation_measure computes individual correlation matrices.

correlation_matrices = correlation_measure.fit_transform(children)

# All individual coefficients are stacked in a unique 2D matrix.
print(
    "Correlations of children are stacked "
    f"in an array of shape {correlation_matrices.shape}"
)
[ConnectivityMeasure.wrapped] Finished fit
Correlations of children are stacked in an array of shape (24, 39, 39)

as well as the average correlation across all fitted subjects.

Mean correlation has shape (39, 39).

We display the connectome matrices of the first 3 children

import numpy as np
from matplotlib import pyplot as plt

_, axes = plt.subplots(1, 3, figsize=(15, 5))
vmax = np.absolute(correlation_matrices).max()
for i, (matrix, ax) in enumerate(
    zip(correlation_matrices, axes, strict=False)
):
    plot_matrix(
        matrix,
        tri="lower",
        axes=ax,
        title=f"correlation, child {i}",
        vmax=vmax,
        vmin=-vmax,
    )
correlation, child 0, correlation, child 1, correlation, child 2

The blocks structure that reflect functional networks are visible.

Now we display as a connectome the mean correlation matrix over all children.

plot_connectome(
    mean_correlation_matrix,
    msdl_coords,
    title="mean correlation over all children",
)
plot group level connectivity
<nilearn.plotting.displays._projectors.OrthoProjector object at 0x7f92c2f16f80>

Studying partial correlations

We can also study direct connections, revealed by partial correlation coefficients. We just change the ConnectivityMeasure kind

[ConnectivityMeasure.wrapped] Finished fit

Most of direct connections are weaker than full connections.

_, axes = plt.subplots(1, 3, figsize=(15, 5))
vmax = np.absolute(partial_correlation_matrices).max()
for i, (matrix, ax) in enumerate(
    zip(partial_correlation_matrices, axes, strict=False)
):
    plot_matrix(
        matrix,
        tri="lower",
        axes=ax,
        title=f"partial correlation, child {i}",
        vmax=vmax,
        vmin=-vmax,
    )
partial correlation, child 0, partial correlation, child 1, partial correlation, child 2
plot_connectome(
    partial_correlation_measure.mean_,
    msdl_coords,
    title="mean partial correlation over all children",
)
plot group level connectivity
<nilearn.plotting.displays._projectors.OrthoProjector object at 0x7f92c2382aa0>

Extract subjects variabilities around a group connectivity

We can use both correlations and partial correlations to capture reproducible connectivity patterns at the group-level. This is done by the tangent space embedding.

tangent_measure = ConnectivityMeasure(kind="tangent", verbose=1)

We fit our children group and get the group connectivity matrix stored as in tangent_measure.mean_, and individual deviation matrices of each subject from it.

tangent_matrices model individual connectivities as perturbations of the group connectivity matrix tangent_measure.mean_. Keep in mind that these subjects-to-group variability matrices do not directly reflect individual brain connections. For instance negative coefficients can not be interpreted as anticorrelated regions.

_, axes = plt.subplots(1, 3, figsize=(15, 5))
for i, (matrix, ax) in enumerate(zip(tangent_matrices, axes, strict=False)):
    plot_matrix(
        matrix,
        tri="lower",
        axes=ax,
        title=f"tangent offset, child {i}",
    )
tangent offset, child 0, tangent offset, child 1, tangent offset, child 2

The average tangent matrix cannot be interpreted, as individual matrices represent deviations from the mean, which is set to 0.

What kind of connectivity is most powerful for classification?

We will use connectivity matrices as features to distinguish children from adults. We use cross-validation and measure classification accuracy to compare the different kinds of connectivity matrices. We use random splits of the subjects into training/testing sets. StratifiedShuffleSplit allows preserving the proportion of children in the test set.

from sklearn.metrics import accuracy_score
from sklearn.model_selection import StratifiedShuffleSplit
from sklearn.svm import LinearSVC

kinds = ["correlation", "partial correlation", "tangent"]
_, classes = np.unique(groups, return_inverse=True)
cv = StratifiedShuffleSplit(n_splits=15, random_state=0, test_size=5)
pooled_subjects = np.asarray(pooled_subjects)

scores = {}
for kind in kinds:
    scores[kind] = []
    for train, test in cv.split(pooled_subjects, classes):
        # *ConnectivityMeasure* can output the estimated subjects coefficients
        # as a 1D arrays through the parameter *vectorize*.
        connectivity = ConnectivityMeasure(
            kind=kind, vectorize=True, verbose=1
        )
        # build vectorized connectomes for subjects in the train set
        connectomes = connectivity.fit_transform(pooled_subjects[train])
        # fit the classifier
        classifier = LinearSVC(dual=True).fit(connectomes, classes[train])
        # make predictions for the left-out test subjects
        predictions = classifier.predict(
            connectivity.transform(pooled_subjects[test])
        )
        # store the accuracy for this cross-validation fold
        scores[kind].append(accuracy_score(classes[test], predictions))
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit
[ConnectivityMeasure.wrapped] Finished fit

display the results

mean_scores = [np.mean(scores[kind]) for kind in kinds]
scores_std = [np.std(scores[kind]) for kind in kinds]

plt.figure(figsize=(6, 4), constrained_layout=True)

positions = np.arange(len(kinds)) * 0.1 + 0.1
plt.barh(positions, mean_scores, align="center", height=0.05, xerr=scores_std)
yticks = [k.replace(" ", "\n") for k in kinds]
plt.yticks(positions, yticks)
plt.gca().grid(True)
plt.gca().set_axisbelow(True)
plt.gca().axvline(0.8, color="red", linestyle="--")
plt.xlabel("Classification accuracy\n(red line = chance level)")
plot group level connectivity
Text(0.5, 34.367, 'Classification accuracy\n(red line = chance level)')

This is a small example to showcase nilearn features. In practice such comparisons need to be performed on much larger cohorts and several datasets. Dadi et al.[1] showed that across many cohorts and clinical questions, the tangent kind should be preferred.

show()

References

Total running time of the script: (2 minutes 31.811 seconds)

Estimated memory usage: 864 MB

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